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Search Results for " withaferin a "

10

Compounds

Cat No. Product Name Synonyms Targets
T5687 WITHAFERIN A Ferroptosis , NF-κB
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer.
T36893 4-oxo Withaferin A
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1...
T35647 4-oxo-27-TBDMS Withaferin A
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/...
TN1230 27-O-acetyl-withaferin A Others
27-O-acetyl-withaferin A is a natural product
T83358 3-Ethylthio withaferin A
3-Ethylthio withaferin A, a derivative of Withaferin A, is a compound known for its inhibitory action on NF-κB (NF-kB).
T83319 4-epi-Withaferin A
4-epi-Withaferin A (compound 28), an analogue of Withaferin A, exhibits enhanced cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). It shows promise for the investigation of protein aggregation-associate...
T83316 4-Methyl withaferin A
4-Methylwithaferin A, a withaferin A analog, exhibits antitumor activity [1].
T83332 4,27-Dimethyl withaferin A
4,27-Dimethyl withaferin A, a synthetic analog of withanolide natural products, exhibits potential in the study of neurodegenerative diseases[1].
T75491 3-(2-Hydroxyethyl) thio withaferin A
3-(2-Hydroxyethyl) thio withaferin A, a derivative of Withaferin A, is a steroidal lactone that inhibits NF-kB activation and targets vimentin, showcasing potent anti-inflammatory and anticancer properties. It also acts ...
T75490 27-O-(tert-Butyldimethylsilyl)withaferin A
27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide known for inducing apoptosis, exhibits antiproliferative effects on HeLa, A-549, and MCF-7 human cancer cell lines, as well as on normal Ver...
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