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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5687 | WITHAFERIN A | Ferroptosis , NF-κB | |
WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer. | |||
T36893 | 4-oxo Withaferin A | ||
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1... | |||
T35647 | 4-oxo-27-TBDMS Withaferin A | ||
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/... | |||
TN1230 | 27-O-acetyl-withaferin A | Others | |
27-O-acetyl-withaferin A is a natural product | |||
T83358 | 3-Ethylthio withaferin A | ||
3-Ethylthio withaferin A, a derivative of Withaferin A, is a compound known for its inhibitory action on NF-κB (NF-kB). | |||
T83319 | 4-epi-Withaferin A | ||
4-epi-Withaferin A (compound 28), an analogue of Withaferin A, exhibits enhanced cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). It shows promise for the investigation of protein aggregation-associate... | |||
T83316 | 4-Methyl withaferin A | ||
4-Methylwithaferin A, a withaferin A analog, exhibits antitumor activity [1]. | |||
T83332 | 4,27-Dimethyl withaferin A | ||
4,27-Dimethyl withaferin A, a synthetic analog of withanolide natural products, exhibits potential in the study of neurodegenerative diseases[1]. | |||
T75491 | 3-(2-Hydroxyethyl) thio withaferin A | ||
3-(2-Hydroxyethyl) thio withaferin A, a derivative of Withaferin A, is a steroidal lactone that inhibits NF-kB activation and targets vimentin, showcasing potent anti-inflammatory and anticancer properties. It also acts ... | |||
T75490 | 27-O-(tert-Butyldimethylsilyl)withaferin A | ||
27-O-(tert-Butyldimethylsilyl)withaferin A (compound 9a), a natural withanolide known for inducing apoptosis, exhibits antiproliferative effects on HeLa, A-549, and MCF-7 human cancer cell lines, as well as on normal Ver... |